BAIT

ZUFSP

C6orf113, dJ412I7.3, RP3-412I7.3
zinc finger with UFM1-specific peptidase domain
UPS Project
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

SSBP1

Mt-SSB, SOSS-B1, SSBP, mtSSB
single-stranded DNA binding protein 1, mitochondrial
GO Process (1)
GO Function (3)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

A family of unconventional deubiquitinases with modular chain specificity determinants.

Hermanns T, Pichlo C, Woiwode I, Klopffleisch K, Witting KF, Ovaa H, Baumann U, Hofmann K

Deubiquitinating enzymes (DUBs) regulate ubiquitin signaling by trimming ubiquitin chains or removing ubiquitin from modified substrates. Similar activities exist for ubiquitin-related modifiers, although the enzymes involved are usually not related. Here, we report human ZUFSP (also known as ZUP1 and C6orf113) and fission yeast Mug105 as founding members of a DUB family different from the six known DUB classes. The crystal ... [more]

Nat Commun Dec. 23, 2017; 9(1);799 [Pubmed: 29476094]

Throughput

  • Low Throughput

Curated By

  • BioGRID