ARC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CAMK2B
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [ISO]
- activation of meiosis involved in egg activation [ISO]
- calcium ion transport [ISO]
- cell projection morphogenesis [IMP]
- inhibitory G-protein coupled receptor phosphorylation [ISO]
- long-term synaptic potentiation [IMP]
- neuromuscular process controlling balance [ISO]
- peptidyl-serine phosphorylation [ISO]
- positive regulation of apoptotic signaling pathway [ISO]
- positive regulation of dendritic spine morphogenesis [IMP]
- positive regulation of neuron projection development [IMP]
- positive regulation of phospholipase A2 activity [IDA]
- positive regulation of synapse maturation [IMP]
- protein autophosphorylation [ISO, ISS]
- regulation of long-term neuronal synaptic plasticity [ISO]
- regulation of synaptic transmission, cholinergic [ISO]
- response to cadmium ion [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Dynamic Arc SUMOylation and Selective Interaction with F-Actin-Binding Protein Drebrin A in LTP Consolidation In Vivo.
Activity-regulatedcytoskeleton-associated protein (Arc) protein is implicated as a master regulator of long-term forms of synaptic plasticity and memory formation, but the mechanisms controlling Arc protein function are little known. Post-translation modification by small ubiquitin-like modifier (SUMO) proteins has emerged as a major mechanism for regulating protein-protein interactions and function. We first show in cell lines that ectopically expressed Arc undergoes ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CAMK2B ARC | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID