BAIT
RTN4R
NgR, NgR1, Nogor
reticulon 4 receptor
GO Process (2)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
FGFR1
Fibroblast growth factor receptor 1
GO Process (53)
GO Function (10)
GO Component (2)
Gene Ontology Biological Process
- angiogenesis [ISO]
- auditory receptor cell development [ISO]
- blood vessel morphogenesis [ISO]
- brain development [ISO]
- branching involved in salivary gland morphogenesis [ISO]
- cell maturation [ISO]
- central nervous system neuron development [IMP]
- chondrocyte differentiation [ISO]
- embryonic limb morphogenesis [ISO]
- fibroblast growth factor receptor signaling pathway [ISO, ISS]
- fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [ISO]
- generation of neurons [ISO]
- in utero embryonic development [ISO]
- inner ear morphogenesis [ISO]
- lung development [ISO]
- lung-associated mesenchyme development [ISO]
- mesenchymal cell differentiation [ISO]
- midbrain development [ISO]
- middle ear morphogenesis [ISO]
- motogenic signaling involved in postnatal olfactory bulb interneuron migration [IMP]
- negative regulation of gene expression [ISO]
- negative regulation of osteoblast differentiation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- neuron projection development [IDA]
- orbitofrontal cortex development [ISO]
- organ induction [ISO]
- outer ear morphogenesis [ISO]
- paraxial mesoderm development [ISO]
- peptidyl-tyrosine phosphorylation [ISO, ISS]
- positive regulation of MAP kinase activity [ISO, ISS]
- positive regulation of MAPK cascade [ISO]
- positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [ISO]
- positive regulation of cardiac muscle cell proliferation [ISO]
- positive regulation of cell cycle [ISO]
- positive regulation of cell proliferation [ISO, ISS]
- positive regulation of mesenchymal cell proliferation [IMP, ISO]
- positive regulation of neuron differentiation [ISO, ISS]
- positive regulation of neuron projection development [IDA, ISO]
- positive regulation of phospholipase C activity [ISO, ISS]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- protein autophosphorylation [ISO, ISS]
- regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [ISO]
- regulation of cell proliferation [IDA, ISO]
- regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- regulation of gene expression [ISO]
- regulation of lateral mesodermal cell fate specification [ISO]
- regulation of sensory perception of pain [IMP]
- regulation of stem cell proliferation [IMP]
- salivary gland morphogenesis [ISO]
- sensory perception of sound [ISO]
- stem cell maintenance [IMP]
- ureteric bud development [ISO]
- ventricular zone neuroblast division [ISO]
Gene Ontology Molecular Function- cell adhesion molecule binding [IPI]
- fibroblast growth factor binding [ISO, ISS]
- fibroblast growth factor-activated receptor activity [ISO, ISS, TAS]
- glycoprotein binding [IDA]
- heparin binding [ISO, ISS]
- identical protein binding [ISO]
- protein binding [IPI]
- protein complex binding [IPI]
- protein homodimerization activity [ISO]
- protein tyrosine kinase activity [ISO]
- cell adhesion molecule binding [IPI]
- fibroblast growth factor binding [ISO, ISS]
- fibroblast growth factor-activated receptor activity [ISO, ISS, TAS]
- glycoprotein binding [IDA]
- heparin binding [ISO, ISS]
- identical protein binding [ISO]
- protein binding [IPI]
- protein complex binding [IPI]
- protein homodimerization activity [ISO]
- protein tyrosine kinase activity [ISO]
Gene Ontology Cellular Component
Rattus norvegicus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Synaptic function for the Nogo-66 receptor NgR1: regulation of dendritic spine morphology and activity-dependent synaptic strength.
In the mature nervous system, changes in synaptic strength correlate with changes in neuronal structure. Members of the Nogo-66 receptor family have been implicated in regulating neuronal morphology. Nogo-66 receptor 1 (NgR1) supports binding of the myelin inhibitors Nogo-A, MAG (myelin-associated glycoprotein), and OMgp (oligodendrocyte myelin glycoprotein), and is important for growth cone collapse in response to acutely presented inhibitors ... [more]
J. Neurosci. Mar. 12, 2008; 28(11);2753-65 [Pubmed: 18337405]
Throughput
- Low Throughput
Curated By
- BioGRID