BAIT

CBFA2T3

ETO2, MTG16, MTGR2, ZMYND4
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
GO Process (3)
GO Function (2)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

LDHA

GSD11, HEL-S-133P, LDH1, LDHM, PIG19
lactate dehydrogenase A
Human Papilloma Virus (HPV) Project
Homo sapiens

Co-localization

Interaction inferred from two proteins that co-localize in the cell by indirect immunofluorescence only when in addition, if one gene is deleted, the other protein becomes mis-localized. Also includes co-dependent association of proteins with promoter DNA in chromatin immunoprecipitation experiments.

Publication

Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1.

Kumar P, Gullberg U, Olsson I, Ajore R

The myeloid translocation gene 16 (MTG16) co-repressor down regulates expression of multiple glycolytic genes, which are targets of the hypoxia-inducible factor 1 (HIF1) heterodimer transcription factor that is composed of oxygen-regulated labile HIF1α and stable HIF1β subunits. For this reason, we investigated whether MTG16 might regulate HIF1 negatively contributing to inhibition of glycolysis and stimulation of mitochondrial respiration. A doxycycline ... [more]

PLoS ONE May. 15, 2015; 10(5);e0123725 [Pubmed: 25974097]

Throughput

  • Low Throughput

Additional Notes

  • ChIP

Curated By

  • BioGRID