BAIT

ST7

ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7
suppression of tumorigenicity 7
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

MYOT

LGMD1, LGMD1A, MFM3, TTID, TTOD
myotilin
GO Process (1)
GO Function (3)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways.

Battle MA, Maher VM, McCormick JJ

In 1997, McCormick and co-workers identified a novel putative tumor suppressor gene, designated ST7, encoding a unique protein with transmembrane receptor characteristics [Qing et al. (1999) Oncogene 18, 335-342]. Using degenerate primers corresponding to the highly conserved region of the ligand-binding domains of members of the low-density lipoprotein receptor (LDLR) superfamily, Ishii et al. [Genomics (1998) 51, 132-135] discovered a ... [more]

Biochemistry Jun. 24, 2003; 42(24);7270-82 [Pubmed: 12809483]

Throughput

  • Low Throughput

Curated By

  • BioGRID