BAIT

CENPM

C22orf18, CENP-M, PANE1, bK250D10.2, CTA-250D10.18-008
centromere protein M
GO Process (1)
GO Function (0)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens
PREY

APITD1

CENP-S, CENPS, FAAP16, MHF1
apoptosis-inducing, TAF9-like domain 1
Fanconi Anemia Project
Homo sapiens

FRET

An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.

Publication

The CENP-T C-terminus is exclusively proximal to H3.1 and not to H3.2 or H3.3.

Abendroth C, Hofmeister A, Hake SB, Kamweru PK, Miess E, Dornblut C, Kueffner I, Deng W, Leonhardt H, Orthaus S, Hoischen C, Diekmann S

The kinetochore proteins assemble onto centromeric chromatin and regulate DNA segregation during cell division. The inner kinetochore proteins bind centromeres while most outer kinetochore proteins assemble at centromeres during mitosis, connecting the complex to microtubules. The centromere-kinetochore complex contains specific nucleosomes and nucleosomal particles. CENP-A replaces canonical H3 in centromeric nucleosomes, defining centromeric chromatin. Next to CENP-A, the CCAN multi-protein ... [more]

Int J Mol Sci Mar. 12, 2015; 16(3);5839-63 [Pubmed: 25775162]

Throughput

  • Low Throughput

Curated By

  • BioGRID