BAIT
CPEB2
CPE-BP2, CPEB-2, hCPEB-2
cytoplasmic polyadenylation element binding protein 2
GO Process (7)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
- cellular response to arsenic-containing substance [ISS]
- cellular response to hypoxia [IDA]
- cellular response to insulin stimulus [IDA]
- cellular response to oxidative stress [ISS]
- negative regulation of GTPase activity [ISS]
- negative regulation of cytoplasmic translation [IMP]
- negative regulation of cytoplasmic translational elongation [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
GABBR1
GABABR1, GABBR1-3, GB1, GPRC3A, dJ271M21.1.1, dJ271M21.1.2, DAAP-188P13.3
gamma-aminobutyric acid (GABA) B receptor, 1
GO Process (4)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
CPEB2-eEF2 interaction impedes HIF-1α RNA translation.
Translation of mRNA into protein proceeds in three phases: initiation, elongation, and termination. Regulated translation allows the prompt production of selective proteins in response to physiological needs and is often controlled by sequence-specific RNA-binding proteins that function at initiation. Whether the elongation phase of translation can be modulated individually by trans-acting factors to synthesize polypeptides at variable rates remains to ... [more]
EMBO J. Feb. 15, 2012; 31(4);959-71 [Pubmed: 22157746]
Throughput
- Low Throughput
Curated By
- BioGRID