RSAD2
Gene Ontology Biological Process
- CD4-positive, alpha-beta T cell activation [ISS]
- CD4-positive, alpha-beta T cell differentiation [ISS]
- defense response to virus [IDA]
- negative regulation of protein secretion [IDA]
- negative regulation of viral genome replication [IDA]
- positive regulation of T-helper 2 cell cytokine production [ISS]
- positive regulation of toll-like receptor 7 signaling pathway [ISS]
- positive regulation of toll-like receptor 9 signaling pathway [ISS]
- response to virus [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
FAM96A
Gene Ontology Biological Process
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Cellular requirements for iron-sulfur cluster insertion into the antiviral radical SAM protein viperin.
Viperin (RSAD2) is an interferon-stimulated antiviral protein that belongs to the radical S-adenosylmethionine (SAM) enzyme family. Viperin's iron-sulfur (Fe/S) cluster is critical for its antiviral activity against many different viruses. CIA1 (CIAO1), an essential component of the cytosolic iron-sulfur protein assembly (CIA) machinery, is crucial for Fe/S cluster insertion into viperin and hence for viperin's antiviral activity. In the CIA ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID