meiosis-specific cyclin Rem1
GO Process (3)
GO Function (1)
GO Component (3)
Schizosaccharomyces pombe (972h)

Synthetic Lethality

A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.


A meiosis-specific cyclin regulated by splicing is required for proper progression through meiosis.

Malapeira J, Moldon A, Hidalgo E, Smith GR, Nurse P, Ayte J

The meiotic cell cycle is modified from the mitotic cell cycle by having a premeiotic S phase which leads to high levels of recombination, a reductional pattern of chromosome segregation at the first division, and a second division with no intervening DNA synthesis. Cyclin-dependent kinases are essential for progression through the meiotic cell cycle, as for the mitotic cycle. Here ... [more]

Mol. Cell. Biol. Aug. 01, 2005; 25(15);6330-7 [Pubmed: 16024772]


  • Low Throughput

Ontology Terms

  • phenotype: inviable (APO:0000112)

Curated By

  • BioGRID