BAIT
PLO1
SPAC23C11.16
Polo kinase Plo1
GO Process (9)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
- mitotic actomyosin contractile ring assembly [IMP]
- mitotic cytokinesis, site selection [IMP]
- positive regulation of barrier septum assembly [IMP]
- positive regulation of protein export from nucleus [IMP]
- positive regulation of septation initiation signaling [IMP]
- regulation of mitotic cytokinesis [IMP]
- regulation of protein localization to mitotic spindle pole body [IMP]
- septation initiation signaling [IMP]
- spindle assembly involved in mitosis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
POM1
SPAC2F7.03c
DYRK family protein kinase Pom1
GO Process (11)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- actin filament bundle distribution [TAS]
- activation of bipolar cell growth [IMP]
- cell morphogenesis involved in conjugation with cellular fusion [IMP]
- cellular protein localization [IMP]
- establishment of mitotic actomyosin contractile ring localization [IMP]
- negative regulation of G2/M transition of mitotic cell cycle [IGI, IMP]
- negative regulation of establishment of actomyosin contractile ring localization [TAS]
- protein localization to medial cortex [IMP]
- regulation of cell size [IGI]
- regulation of establishment or maintenance of cell polarity regulating cell shape [IMP]
- signal transduction [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Role of polo kinase and Mid1p in determining the site of cell division in fission yeast.
The fission yeast Schizosaccharomyces pombe divides symmetrically using a medial F-actin- based contractile ring to produce equal-sized daughter cells. Mutants defective in two previously described genes, mid1 and pom1, frequently divide asymmetrically. Here we present the identification of three new temperature-sensitive mutants defective in localization of the division plane. All three mutants have mutations in the polo kinase gene, plo1, ... [more]
J. Cell Biol. Dec. 14, 1998; 143(6);1603-16 [Pubmed: 9852154]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
- phenotype: heat sensitivity (APO:0000147)
Curated By
- BioGRID