BSG
Gene Ontology Biological Process
- blood coagulation [TAS]
- cell surface receptor signaling pathway [TAS]
- cellular metabolic process [TAS]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- leukocyte migration [TAS]
- protein targeting to plasma membrane [ISS]
- pyruvate metabolic process [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TUBA4A
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
F-Box Protein FBXO22 Mediates Polyubiquitination and Degradation of CD147 to Reverse Cisplatin Resistance of Tumor Cells.
Drug resistance remains a major clinical obstacle to successful treatment of cancer. As posttranslational modification is becoming widely recognized to affect the function of oncoproteins, targeting specific posttranslational protein modification provides an attractive strategy for anticancer drug development. CD147 is a transmembrane glycoprotein contributing to chemo-resistance of cancer cells in a variety of human malignancies. Ubiquitination is an important posttranslational ... [more]
Throughput
- High Throughput
Additional Notes
- TUBA1A(ETG7846)
- TUBA1B(ETG10376)
- TUBA1C(ETG84790)
- TUBA3C(ETG7278)
- TUBA3D(ETG113457)
- TUBA3E(ETG112714)
- TUBA4A(ETG7277)
- TUBA4B(ETG80086)
- TUBA8(ETG51807)
- The article text identifies the hit protein as alpha tubulin which is ambiguous and could refer to any of the following:
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
BSG TUBA4A | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.783 | BioGRID | 3161901 |
Curated By
- BioGRID