BAIT
TRIM14
tripartite motif containing 14
GO Process (4)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Homo sapiens
PREY
ATP5F1
PIG47, RP11-552M11.5
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
GO Process (7)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- extracellular vesicular exosome [IDA]
- membrane [IDA]
- mitochondrial inner membrane [TAS]
- mitochondrial matrix [NAS]
- mitochondrial proton-transporting ATP synthase complex [IDA]
- mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [IBA]
- mitochondrion [IDA]
- nucleoplasm [IDA]
- nucleus [IDA]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling.
Mitochondrial antiviral signaling platform protein (MAVS) acts as a central hub for RIG-I receptor proximal signal propagation. However, key components in the assembly of the MAVS mitochondrial platform that promote RIG-I mitochondrial localization and optimal activation are still largely undefined. Employing pooled RNAi and yeast two-hybrid screenings, we report that the mitochondrial adaptor protein tripartite motif (TRIM)14 provides a docking ... [more]
Mol. Cell Oct. 19, 2017; 68(2);293-307.e5 [Pubmed: 29053956]
Throughput
- High Throughput
Curated By
- BioGRID