BAIT
MAPK6
ERK3, HsT17250, PRKM6, p97MAPK
mitogen-activated protein kinase 6
GO Process (3)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
CDIPT
PIS, PIS1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
GO Process (4)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways.
Amino acid hydroxylation is a post-translational modification that regulates intra- and inter-molecular protein-protein interactions. The modifications are regulated by a family of 2-oxoglutarate- (2OG) dependent enzymes and, although the biochemistry is well understood, until now only a few substrates have been described for these enzymes. Using quantitative interaction proteomics, we screened for substrates of the proline hydroxylase PHD3 and the ... [more]
Cell Rep Mar. 22, 2016; 14(11);2745-60 [Pubmed: 26972000]
Throughput
- High Throughput
Additional Notes
- Source of MAPK6 not clear
Curated By
- BioGRID