BAIT
TMPO
CMD1T, LAP2, LEMD4, PRO0868, TP
thymopoietin
GO Process (0)
GO Function (2)
GO Component (5)
Gene Ontology Molecular Function
Homo sapiens
PREY
LRPPRC
CLONE-23970, GP130, LRP130, LSFC
leucine-rich pentatricopeptide repeat containing
GO Process (1)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.
Nonalcoholic fatty liver disease (NAFLD) is becoming the major chronic liver disease in many countries. Its pathogenesis is multifactorial, but twin and familial studies indicate significant heritability, which is not fully explained by currently known genetic susceptibility loci. Notably, mutations in genes encoding nuclear lamina proteins, including lamins, cause lipodystrophy syndromes that include NAFLD. We hypothesized that variants in lamina-associated ... [more]
Hepatology May. 01, 2018; 67(5);1710-1725 [Pubmed: 28902428]
Throughput
- High Throughput
Curated By
- BioGRID