BAIT

PPEF1

PP7, PPEF, PPP7C, PPP7CA, RP3-499B10.1
protein phosphatase, EF-hand calcium binding domain 1
GO Process (4)
GO Function (2)
GO Component (1)
Homo sapiens
PREY

LRPPRC

CLONE-23970, GP130, LRP130, LSFC
leucine-rich pentatricopeptide repeat containing
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

Yadav L, Tamene F, Goeoes H, van Drogen A, Katainen R, Aebersold R, Gstaiger M, Varjosalo M

Coordinated activities of protein kinases and phosphatases ensure phosphorylation homeostasis, which, when perturbed, can instigate diseases, including cancer. Yet, in contrast to kinases, much less is known about protein phosphatase functions and their interactions and complexes. Here, we used quantitative affinity proteomics to assay protein-protein interactions for 54 phosphatases distributed across the three major protein phosphatase families, with additional analysis ... [more]

Cell Syst Apr. 26, 2017; 4(4);430-444.e5 [Pubmed: 28330616]

Throughput

  • High Throughput

Curated By

  • BioGRID