BAIT

PPP2R2C

B55-GAMMA, IMYPNO, IMYPNO1, PR52, PR55G
protein phosphatase 2, regulatory subunit B, gamma
GO Process (1)
GO Function (2)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

ATAD3A

RP5-832C2.1
ATPase family, AAA domain containing 3A
GO Process (2)
GO Function (0)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

Yadav L, Tamene F, Goeoes H, van Drogen A, Katainen R, Aebersold R, Gstaiger M, Varjosalo M

Coordinated activities of protein kinases and phosphatases ensure phosphorylation homeostasis, which, when perturbed, can instigate diseases, including cancer. Yet, in contrast to kinases, much less is known about protein phosphatase functions and their interactions and complexes. Here, we used quantitative affinity proteomics to assay protein-protein interactions for 54 phosphatases distributed across the three major protein phosphatase families, with additional analysis ... [more]

Cell Syst Apr. 26, 2017; 4(4);430-444.e5 [Pubmed: 28330616]

Throughput

  • High Throughput

Curated By

  • BioGRID