BAIT
RUNX3
AML2, CBFA3, PEBP2aC, RP3-398I9.1
runt-related transcription factor 3
GO Process (7)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- negative regulation of cell cycle [ISS]
- negative regulation of epithelial cell proliferation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- peripheral nervous system neuron development [TAS]
- protein phosphorylation [IDA]
- regulation of transcription, DNA-templated [NAS]
- transcription from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PVT1
LINC00079, NCRNA00079
Pvt1 oncogene (non-protein coding)
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
HOTAIR induces the ubiquitination of Runx3 by interacting with Mex3b and enhances the invasion of gastric cancer cells.
Long non-coding RNAs (LncRNAs) exert their functions mainly by binding to their corresponding proteins. Runt-related transcription factor 3 (Runx3) is an important transcription factor that functions as a tumor suppressor in gastric cancer. Whether there is an interplay between LncRNAs and Runx3 remains unclear.RPISeq was applied to screen the LncRNAs that potentially bind to Runx3. The interaction between LncRNA HOX ... [more]
Gastric Cancer Feb. 07, 2018; (); [Pubmed: 29417297]
Throughput
- Low Throughput
Curated By
- BioGRID