BAIT
FGFR1
BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1
fibroblast growth factor receptor 1
GO Process (25)
GO Function (7)
GO Component (5)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- MAPK cascade [TAS]
- axon guidance [TAS]
- cell migration [TAS]
- chordate embryonic development [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [IDA, IGI, IPI, TAS]
- innate immune response [TAS]
- insulin receptor signaling pathway [TAS]
- neuron migration [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- peptidyl-tyrosine phosphorylation [IDA]
- phosphatidylinositol-mediated signaling [TAS]
- positive regulation of MAP kinase activity [IDA]
- positive regulation of MAPK cascade [IMP]
- positive regulation of cell proliferation [IDA, IGI, IMP]
- positive regulation of neuron differentiation [IMP]
- positive regulation of phosphatidylinositol 3-kinase signaling [TAS]
- positive regulation of phospholipase C activity [IDA]
- positive regulation of phospholipase activity [TAS]
- protein autophosphorylation [IDA]
- protein phosphorylation [NAS]
- regulation of cell differentiation [TAS]
- skeletal system development [TAS]
- skeletal system morphogenesis [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PHB
HEL-215, HEL-S-54e, PHB1
prohibitin
GO Process (15)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- cellular response to interleukin-6 [IDA]
- histone deacetylation [IDA]
- negative regulation of androgen receptor signaling pathway [IDA, IMP]
- negative regulation of cell growth [IMP]
- negative regulation of cell proliferation [IMP]
- negative regulation of glucocorticoid receptor signaling pathway [IDA]
- negative regulation of transcription by competitive promoter binding [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- osteoblast differentiation [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- progesterone receptor signaling pathway [IDA]
- regulation of apoptotic process [TAS]
- regulation of transcription, DNA-templated [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Protein partners in the life history of activated fibroblast growth factor receptors.
Fibroblast growth factor receptors (FGFRs) are a family of four transmembrane (TM) receptor tyrosine kinases (RTKs) which bind to a large family of fibroblast growth factor (FGF) ligands with varying affinity and specificity. FGFR signaling regulates many physiological and pathological processes in development and tissue homeostasis. Understanding FGFR signaling processes requires the identification of partner proteins which regulate receptor function ... [more]
Proteomics Dec. 01, 2007; 7(24);4565-78 [Pubmed: 18022941]
Throughput
- High Throughput
Curated By
- BioGRID