BAIT
FGFR1
BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1
fibroblast growth factor receptor 1
GO Process (25)
GO Function (7)
GO Component (5)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- MAPK cascade [TAS]
- axon guidance [TAS]
- cell migration [TAS]
- chordate embryonic development [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [IDA, IGI, IPI, TAS]
- innate immune response [TAS]
- insulin receptor signaling pathway [TAS]
- neuron migration [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- peptidyl-tyrosine phosphorylation [IDA]
- phosphatidylinositol-mediated signaling [TAS]
- positive regulation of MAP kinase activity [IDA]
- positive regulation of MAPK cascade [IMP]
- positive regulation of cell proliferation [IDA, IGI, IMP]
- positive regulation of neuron differentiation [IMP]
- positive regulation of phosphatidylinositol 3-kinase signaling [TAS]
- positive regulation of phospholipase C activity [IDA]
- positive regulation of phospholipase activity [TAS]
- protein autophosphorylation [IDA]
- protein phosphorylation [NAS]
- regulation of cell differentiation [TAS]
- skeletal system development [TAS]
- skeletal system morphogenesis [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TH
DYT14, DYT5b, TYH
tyrosine hydroxylase
GO Process (22)
GO Function (3)
GO Component (9)
Gene Ontology Biological Process
- anatomical structure morphogenesis [TAS]
- catecholamine biosynthetic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- dopamine biosynthetic process [IDA]
- dopamine biosynthetic process from tyrosine [NAS]
- embryonic camera-type eye morphogenesis [ISS]
- epinephrine biosynthetic process [IDA]
- eye photoreceptor cell development [ISS]
- heart development [ISS]
- heart morphogenesis [NAS]
- learning [ISS]
- locomotory behavior [ISS]
- memory [ISS]
- norepinephrine biosynthetic process [IDA]
- organ morphogenesis [ISS]
- pigmentation [TAS]
- regulation of heart contraction [ISS]
- response to ethanol [IDA]
- response to hypoxia [IDA]
- small molecule metabolic process [TAS]
- synaptic transmission, dopaminergic [ISS]
- visual perception [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-localization
Interaction inferred from two proteins that co-localize in the cell by indirect immunofluorescence only when in addition, if one gene is deleted, the other protein becomes mis-localized. Also includes co-dependent association of proteins with promoter DNA in chromatin immunoprecipitation experiments.
Publication
A novel nuclear FGF Receptor-1 partnership with retinoid and Nur receptors during developmental gene programming of embryonic stem cells.
FGF Receptor-1 (FGFR1), a membrane-targeted protein, is also involved in independent direct nuclear signaling. We show that nuclear accumulation of FGFR1 is a common response to retinoic acid (RA) in pluripotent embryonic stem cells (ESC) and neural progenitors and is both necessary and sufficient for neuronal-like differentiation and accompanying neuritic outgrowth. Dominant negative nuclear FGFR1, which lacks the tyrosine kinase ... [more]
J. Cell. Biochem. Sep. 01, 2012; 113(9);2920-36 [Pubmed: 22539306]
Throughput
- Low Throughput
Additional Notes
- ChIP
Curated By
- BioGRID