BAIT
CRYL1
GDH, HEL30, lambda-CRY
crystallin, lambda 1
GO Process (0)
GO Function (3)
GO Component (7)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ACAA1
ACAA, PTHIO, THIO
acetyl-CoA acyltransferase 1
GO Process (8)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- alpha-linolenic acid metabolic process [TAS]
- bile acid metabolic process [IMP]
- cellular lipid metabolic process [TAS]
- fatty acid beta-oxidation [IMP]
- fatty acid beta-oxidation using acyl-CoA oxidase [TAS]
- small molecule metabolic process [TAS]
- unsaturated fatty acid metabolic process [TAS]
- very long-chain fatty acid metabolic process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.
Genome-scale expression studies and comprehensive loss-of-function genetic screens have focused almost exclusively on the highest confidence candidate genes. Here, we describe a strategy for characterizing the lower confidence candidates identified by such approaches. We interrogated 177 genes that we classified as essential for the proliferation of cancer cells exhibiting constitutive β-catenin activity and integrated data for each of the candidates, ... [more]
Cell Syst Dec. 28, 2015; 3(3);302-316.e4 [Pubmed: 27684187]
Throughput
- High Throughput
Additional Notes
- High-credibility protein interactions were identified using draft-PPI and a method for protein interaction credibility scoring (ICS).
Curated By
- BioGRID