BAIT
CDC13
SPBC582.03
G2/M B-type cyclin Cdc13
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- cellular response to nitrogen starvation [IMP]
- negative regulation of G0 to G1 transition [IMP]
- negative regulation of induction of conjugation with cellular fusion [IMP]
- positive regulation of protein localization to nucleus [IMP]
- positive regulation of protein serine/threonine kinase activity [IGI]
- regulation of cyclin-dependent protein serine/threonine kinase activity [IMP]
- signal transduction [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
MCS6
cdk7, crk1, mop1, SPBC19F8.07
cyclin-dependent protein kinase/CDK-activating kinase Mcs6
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
cdc2 and the regulation of mitosis: six interacting mcs genes.
A cdc2-3w weel-50 double mutant of fission yeast displays a temperature-sensitive lethal phenotype that is associated with gross abnormalities of chromosome segregation and has been termed mitotic catastrophe. In order to identify new genetic elements that might interact with the cdc2 protein kinase in the regulation of mitosis, we have isolated revertants of the lethal double mutant. The suppressor mutations ... [more]
Genetics Aug. 01, 1989; 122(4);773-82 [Pubmed: 2474475]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Curated By
- BioGRID