A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.

Publication

The Schizosaccharomyces pombe genes sep10 and sep11 encode putative general transcriptional regulators involved in multiple cellular processes.

Szilagyi Z, Grallert A, Nemeth N, Sipiczki M

We have previously described the genetic analysis of eleven complementation groups ( sep6- sep16) defined by Schizosaccharomyces pombe mutants that are defective in cell separation and sexual differentiation. Here we report on the cloning and characterisation of two members of this set, sep10 and sep11. Sequencing of the full-length sep10 revealed a continuous ORF that encodes a conserved protein with ... [more]

Mol. Genet. Genomics Dec. 01, 2002; 268(4);553-62 [Pubmed: 12471453]

Throughput

Low Throughput

Ontology Terms

phenotype: inviable (APO:0000112)

Curated By

BioGRID

Interaction Summary

MED31

Gene Ontology Biological Process

Gene Ontology Cellular Component

MED18

Gene Ontology Molecular Function

protein binding [IPI]