BAIT
RAD54
rhp54, SPAC15A10.03c
DNA-dependent ATPase Rad54/Rhp54
GO Process (5)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
CDC2
cdk1, swo2, tws1, pi002, SPACTOKYO_453.34, wee2, SPBC11B10.09
cyclin-dependent protein kinase Cdk1/Cdc2
GO Process (13)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [IMP]
- cellular response to nitrogen starvation [IMP]
- negative regulation of G0 to G1 transition [IMP]
- negative regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation [IMP]
- negative regulation of induction of conjugation with cellular fusion [EXP]
- positive regulation of G1/S transition of mitotic cell cycle [IMP]
- positive regulation of G2/M transition of mitotic cell cycle [IMP]
- positive regulation of mitotic cytokinesis [IMP]
- positive regulation of septation initiation signaling [IMP]
- regulation of cell size [NAS]
- regulation of meiotic cell cycle [IMP]
- response to intra-S DNA damage checkpoint signaling [IMP]
- traversing start control point of mitotic cell cycle [NAS]
Gene Ontology Molecular Function
Schizosaccharomyces pombe (972h)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Isolation of the Schizosaccharomyces pombe RAD54 homologue, rhp54+, a gene involved in the repair of radiation damage and replication fidelity.
The RAD54 gene of Saccharomyces cerevisiae encodes a putative helicase, which is involved in the recombinational repair of DNA damage. The RAD54 homologue of the fission yeast Schizosaccharomyces pombe, rhp54+, was isolated by using the RAD54 gene as a heterologous probe. The gene is predicted to encode a protein of 852 amino acids. The overall homology between the mutual proteins ... [more]
J. Cell. Sci. Jan. 01, 1996; 109(0);73-81 [Pubmed: 8834792]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Curated By
- BioGRID