BAIT
FXR2
FMR1L2, FXR2P
fragile X mental retardation, autosomal homolog 2
GO Process (1)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
RBM14
COAA, PSP2, SIP, SYTIP1, TMEM137
RNA binding motif protein 14
GO Process (9)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
- DNA recombination [NAS]
- DNA repair [NAS]
- DNA replication [NAS]
- glucocorticoid receptor signaling pathway [NAS]
- histone deacetylation [IPI]
- intracellular estrogen receptor signaling pathway [NAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- response to hormone [TAS]
- transcription from RNA polymerase II promoter [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions.
Knowing which proteins and RNAs directly interact is essential for understanding cellular mechanisms. Unfortunately, discovering such interactions is costly and often unreliable. To overcome these limitations, we developed rec-YnH, a new yeast two and three-hybrid-based screening pipeline capable of detecting interactions within protein libraries or between protein libraries and RNA fragment pools. rec-YnH combines batch cloning and transformation with intracellular ... [more]
Nat Commun Sep. 14, 2018; 9(1);3747 [Pubmed: 30217970]
Throughput
- High Throughput
Additional Notes
- High confidence rec-Y2H protein interactions.
Curated By
- BioGRID