PREY

NDA3

alp12, ben1, SPBC26H8.07c
tubulin beta Nda3
Schizosaccharomyces pombe (972h)

Synthetic Lethality

A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.

Publication

Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis.

Baehler J, Pringle JR

Schizosaccharomyces pombe cells have a well-defined pattern of polarized growth at the cell ends during interphase and divide symmetrically into two equal-sized daughter cells. We identified a gene, pom1, that provides positional information for both growth and division in S. pombe. pom1 mutants form functioning growth zones and division septa but show several abnormalities: (1) After division, cells initiate growth ... [more]

Genes Dev. May. 01, 1998; 12(9);1356-70 [Pubmed: 9573052]

Throughput

  • Low Throughput

Ontology Terms

  • phenotype: inviable (APO:0000112)

Curated By

  • BioGRID