BAIT
POM1
SPAC2F7.03c
DYRK family protein kinase Pom1
GO Process (11)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- actin filament bundle distribution [TAS]
- activation of bipolar cell growth [IMP]
- cell morphogenesis involved in conjugation with cellular fusion [IMP]
- cellular protein localization [IMP]
- establishment of mitotic actomyosin contractile ring localization [IMP]
- negative regulation of G2/M transition of mitotic cell cycle [IGI, IMP]
- negative regulation of establishment of actomyosin contractile ring localization [TAS]
- protein localization to medial cortex [IMP]
- regulation of cell size [IGI]
- regulation of establishment or maintenance of cell polarity regulating cell shape [IMP]
- signal transduction [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
CDC14
SPBC24C6.07
SIN component Cdc14
GO Process (3)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis.
Schizosaccharomyces pombe cells have a well-defined pattern of polarized growth at the cell ends during interphase and divide symmetrically into two equal-sized daughter cells. We identified a gene, pom1, that provides positional information for both growth and division in S. pombe. pom1 mutants form functioning growth zones and division septa but show several abnormalities: (1) After division, cells initiate growth ... [more]
Genes Dev. May. 01, 1998; 12(9);1356-70 [Pubmed: 9573052]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Curated By
- BioGRID