STY1
Gene Ontology Biological Process
- G1 cell cycle arrest in response to nitrogen starvation [IMP]
- G1 to G0 transition [IMP]
- MAPK cascade in response to starvation [IMP]
- MAPK cascade involved in osmosensory signaling pathway [IDA, IMP]
- cellular response to cation stress [IGI]
- cellular response to nitrogen starvation [IMP]
- mRNA export from nucleus in response to heat stress [IMP]
- mitotic cell cycle arrest in response to nitrogen starvation [IMP]
- positive regulation of G2/M transition of mitotic cell cycle [IMP]
- positive regulation of transcription factor import into nucleus in response to oxidative stress [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [IMP]
- regulation of DNA binding [IDA]
- regulation of cAMP-mediated signaling [IMP]
- regulation of cAMP-mediated signaling by regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of cell shape involved in G1 to G0 transition [IMP]
- regulation of chromatin assembly [IMP]
- regulation of chromatin disassembly [IMP]
- regulation of histone acetylation [IMP]
- regulation of mRNA stability involved in cellular response to UV [IMP]
- regulation of meiotic cell cycle [IMP]
- regulation of reciprocal meiotic recombination [IMP]
- regulation of translation in response to nitrogen starvation [IDA]
- regulation of translation in response to osmotic stress [IDA, IMP]
- regulation of translation in response to oxidative stress [IDA, IMP]
- stress granule assembly [IMP]
- stress granule disassembly [IMP]
- stress-activated MAPK cascade [IMP]
Gene Ontology Molecular Function
ATF21
Gene Ontology Biological Process
Gene Ontology Molecular Function
Dosage Rescue
A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene.
Publication
Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast.
The stress-activated Wis1-Spc1 protein kinase cascade links mitotic control with environmental signals in Schizosaccharomyces pombe. Fission yeast spc1- mutants are delayed in G2 during normal growth and undergo G2 arrest when exposed to osmotic or oxidative stress. Here we report that Spc1 also has an important role in regulating sexual development in S. pombe. This discovery arose from the observation ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: mating efficiency (APO:0000034)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| STY1 ATF21 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -4.4774 | BioGRID | 759752 |
Curated By
- BioGRID