BAIT
UBP6
SPAC6G9.08
ubiquitin C-terminal hydrolase Ubp6
GO Process (4)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA]
- nucleus [IDA]
Schizosaccharomyces pombe (972h)
PREY
ATF1
gad7, mts1, sss1, SPNCRNA.353, SPNG1409, SPBC29B5.01
transcription factor, Atf-CREB family Atf1
GO Process (15)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
- activation of reciprocal meiotic recombination [IMP]
- cellular response to nitrogen starvation [IMP]
- cellular response to starvation [IMP]
- mRNA export from nucleus in response to heat stress [IMP]
- negative regulation of G1/S transition of mitotic cell cycle by positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation [IMP]
- negative regulation of antisense RNA transcription [IMP]
- negative regulation of reciprocal meiotic recombination [IMP]
- negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress [IMP]
- nucleosome positioning [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of cAMP-mediated signaling [IMP]
- regulation of histone acetylation by regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of histone methylation by regulation of transcription from RNA polymerase II promoter [IMP]
- transcription from RNA polymerase II promoter [IMP]
Gene Ontology Molecular Function- RNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IMP]
- protein binding [IPI]
- protein heterodimerization activity [IPI]
- recombination hotspot binding [IDA]
- sequence-specific DNA binding [IDA]
- RNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IMP]
- protein binding [IPI]
- protein heterodimerization activity [IPI]
- recombination hotspot binding [IDA]
- sequence-specific DNA binding [IDA]
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26S proteasome in fission yeast.
Conjugation of proteins to ubiquitin plays a central role for a number of cellular processes including endocytosis, DNA repair and degradation by the 26S proteasome. However, ubiquitination is reversible as a number of deubiquitinating enzymes mediate the disassembly of ubiquitin-protein conjugates. Some deubiquitinating enzymes are associated with the 26S proteasome contributing to and regulating the particle's activity. Here, we characterise ... [more]
J. Mol. Biol. Nov. 26, 2004; 344(3);697-706 [Pubmed: 15533439]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Curated By
- BioGRID