TOR1
Gene Ontology Biological Process
- TOR signaling [TAS]
- cell aging [TAS]
- cellular response to nitrogen starvation [IMP]
- cellular response to osmotic stress [IMP]
- phosphatidylinositol-mediated signaling [NAS]
- positive regulation of conjugation with cellular fusion [IMP]
- regulation of conjugation with cellular fusion [IMP]
- response to temperature stimulus [IMP]
Gene Ontology Molecular Function
TSC2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Opposite effects of tor1 and tor2 on nitrogen starvation responses in fission yeast.
The TOR protein kinases exhibit a conserved role in regulating cellular growth and proliferation. In the fission yeast two TOR homologs are present. tor1(+) is required for starvation and stress responses, while tor2(+) is essential. We report here that Tor2 depleted cells show a phenotype very similar to that of wild-type cells starved for nitrogen, including arrest at the G(1) ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| TOR1 TSC2 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 248271 | |
| TOR1 TSC2 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 932943 | |
| TOR1 TSC2 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 248230 |
Curated By
- BioGRID