CG7945
Gene Ontology Biological Process
Gene Ontology Molecular Function
HSC70-4
Gene Ontology Biological Process
- RNA interference [IMP]
- axon guidance [IMP]
- axonal fasciculation [IMP]
- cellular response to topologically incorrect protein [IMP]
- embryonic development via the syncytial blastoderm [IMP]
- mRNA splicing, via spliceosome [IC]
- nervous system development [IMP]
- neurotransmitter secretion [IGI, IMP, IPI]
- protein folding [ISS, NAS]
- vesicle-mediated transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Myeloid Leukemia Factor Acts in a Chaperone Complex to Regulate Transcription Factor Stability and Gene Expression.
Mutations that affect myelodysplasia/myeloid leukemia factor (MLF) proteins are associated with leukemia and several other cancers. However, with no strong homology to other proteins of known function, the role of MLF proteins in the cell has remained elusive. Here, we describe a proteomics approach that identifies MLF as a member of a nuclear chaperone complex containing a DnaJ protein, BCL2-associated ... [more]
Throughput
- Low Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
HSC70-4 CG7945 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |