BAIT

CG7945

CG17014, Dmel\CG7945, Dmel_CG7945
CG7945 gene product from transcript CG7945-RA
GO Process (1)
GO Function (1)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Drosophila melanogaster
PREY

HSC70-4

BAP74, CG4264, Dmel\CG4264, E(csp)1545, E(nd)195, HSC-70, HSC4, HSC70, Hsc-4, Hsc4p, Hsp-c4, Hsp70, Q3KN45_DROME, anon-WO0118547.237, bs17d06.y1, chr3R:11070155..11070315, dhsc70, i190, l(3)03550, l(3)L3929, l(3)j7A4, scd, Dmel_CG4264
Heat shock protein cognate 4
Drosophila melanogaster

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Myeloid Leukemia Factor Acts in a Chaperone Complex to Regulate Transcription Factor Stability and Gene Expression.

Dyer JO, Dutta A, Gogol M, Weake VM, Dialynas G, Wu X, Seidel C, Zhang Y, Florens L, Washburn MP, Abmayr SM, Workman JL

Mutations that affect myelodysplasia/myeloid leukemia factor (MLF) proteins are associated with leukemia and several other cancers. However, with no strong homology to other proteins of known function, the role of MLF proteins in the cell has remained elusive. Here, we describe a proteomics approach that identifies MLF as a member of a nuclear chaperone complex containing a DnaJ protein, BCL2-associated ... [more]

J. Mol. Biol. Jun. 30, 2017; 429(13);2093-2107 [Pubmed: 27984043]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
HSC70-4 CG7945
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

High-BioGRID
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Curated By