BAIT

MOB1

SPBC428.13c
Sid2-Mob1 kinase complex regulatory subunit Mob1
Schizosaccharomyces pombe (972h)
PREY

CDC11

SPCC1739.11c
SIN component scaffold protein, centriolin ortholog Cdc11
GO Process (4)
GO Function (2)
GO Component (4)
Schizosaccharomyces pombe (972h)

Co-localization

Interaction inferred from two proteins that co-localize in the cell by indirect immunofluorescence only when in addition, if one gene is deleted, the other protein becomes mis-localized. Also includes co-dependent association of proteins with promoter DNA in chromatin immunoprecipitation experiments.

Publication

S. pombe cdc11p, together with sid4p, provides an anchor for septation initiation network proteins on the spindle pole body.

Krapp A, Schmidt S, Cano E, Simanis V

BACKGROUND: The signal for the onset of septum formation in the fission yeast Schizosaccharomyces pombe is transduced by the septation initiation network (SIN). Many of the components of the SIN are located on the spindle pole body during mitosis, from where it is presumed that the signal for septum formation is delivered. Cdc11 mutants are defective in SIN signaling, but ... [more]

Curr. Biol. Oct. 16, 2001; 11(20);1559-68 [Pubmed: 11676915]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
MOB1 CDC11
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-
MOB1 CDC11
Synthetic Lethality
Synthetic Lethality

A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.

Low-BioGRID
675063

Curated By

  • BioGRID