WNT5A
Gene Ontology Biological Process
- Wnt signaling pathway [IDA]
- Wnt signaling pathway, calcium modulating pathway [IDA, IMP]
- activation of JUN kinase activity [IDA, IMP]
- activation of MAPK activity [IDA]
- activation of protein kinase B activity [IDA]
- axon guidance [ISS]
- cell fate commitment [IBA]
- cellular protein localization [IDA]
- cellular response to calcium ion [IEP]
- cellular response to interferon-gamma [IEP]
- cellular response to lipopolysaccharide [IEP]
- cellular response to retinoic acid [ISS]
- cellular response to transforming growth factor beta stimulus [IEP]
- embryonic skeletal system development [IMP]
- epithelial to mesenchymal transition [IEP]
- face development [IMP]
- genitalia development [IMP]
- hematopoietic stem cell proliferation [IDA]
- keratinocyte differentiation [IEP]
- lens development in camera-type eye [ISS]
- male gonad development [IEP]
- negative regulation of apoptotic process [IDA]
- negative regulation of canonical Wnt signaling pathway [IDA, IGI]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of mesenchymal cell proliferation [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- neuron differentiation [IBA, ISS]
- olfactory bulb interneuron development [ISS]
- optic cup formation involved in camera-type eye development [ISS]
- palate development [IMP]
- positive regulation of NF-kappaB transcription factor activity [IDA]
- positive regulation of T cell chemotaxis [IMP]
- positive regulation of angiogenesis [IMP]
- positive regulation of cGMP metabolic process [IDA]
- positive regulation of chemokine biosynthetic process [IMP]
- positive regulation of cytokine secretion involved in immune response [IMP]
- positive regulation of endothelial cell migration [IMP]
- positive regulation of endothelial cell proliferation [IMP]
- positive regulation of fibroblast proliferation [IDA]
- positive regulation of inflammatory response [IMP]
- positive regulation of interleukin-1 beta secretion [IMP]
- positive regulation of interleukin-6 production [IMP]
- positive regulation of macrophage activation [IMP]
- positive regulation of macrophage cytokine production [IMP]
- positive regulation of neuron projection development [ISS]
- positive regulation of ossification [IMP]
- positive regulation of protein catabolic process [IGI]
- positive regulation of protein kinase C signaling [IMP]
- positive regulation of response to cytokine stimulus [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription, DNA-templated [IMP]
- positive regulation of type I interferon-mediated signaling pathway [IDA]
- response to organic substance [IEP]
- wound healing [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
LGALS3BP
Gene Ontology Biological Process
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Role of the extracellular matrix-located Mac-2 binding protein as an interactor of the Wnt proteins.
The Wnt proteins constitute a conserved family of secreted palmitoleate-containing signaling proteins that play important roles in development and tissue homeostasis. Their hydrophobic nature has raised the question of how the proteins are transported outside the cells. Accumulating evidence suggests that several different mechanisms, including transport by lipoprotein particles and exosomes, may contribute to this process. Here, we expressed epitope-tagged ... [more]
Throughput
- Low Throughput
Additional Notes
- Mac-2BP from COS-1 cells
Curated By
- BioGRID