REL
Gene Ontology Biological Process
Gene Ontology Molecular Function- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
Gene Ontology Cellular Component
- cytosol [TAS]
- nucleoplasm [TAS]
SDCBP
Gene Ontology Biological Process
- actin cytoskeleton organization [NAS]
- axon guidance [TAS]
- intracellular signal transduction [NAS]
- positive regulation of JNK cascade [IC]
- positive regulation of exosomal secretion [IMP]
- positive regulation of extracellular vesicular exosome assembly [IMP]
- positive regulation of phosphorylation [IDA]
- protein targeting to membrane [NAS]
- substrate-dependent cell migration, cell extension [NAS]
- synaptic transmission [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.
The NF-κB family of transcription factors is pivotal in controlling cellular responses to environmental stresses; abnormal nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling features in many autoimmune diseases and cancers. Several components of the NF-κB signaling pathway have been reported to interact with the protein TNIP2 (also known as ABIN2), and TNIP2 can both positively and negatively regulate ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| REL SDCBP | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID