BAIT
AKTIP
FT1, FTS
AKT interacting protein
GO Process (7)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC25A13
ARALAR2, CITRIN, CTLN2
solute carrier family 25 (aspartate/glutamate carrier), member 13
GO Process (13)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- ATP biosynthetic process [IDA]
- L-aspartate transmembrane transport [IDA]
- L-glutamate transmembrane transport [IDA]
- L-glutamate transport [IDA]
- aspartate transport [IDA]
- carbohydrate metabolic process [TAS]
- cellular respiration [IDA]
- gluconeogenesis [TAS]
- glucose metabolic process [TAS]
- malate-aspartate shuttle [IDA]
- response to calcium ion [IDA]
- small molecule metabolic process [TAS]
- transport [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence.
AKTIP is a shelterin-interacting protein required for replication of telomeric DNA. Here, we show that AKTIP biochemically interacts with A- and B-type lamins and affects lamin A, but not lamin C or B, expression. In interphase cells, AKTIP localizes at the nuclear rim and in discrete regions of the nucleoplasm just like lamins. Double immunostaining revealed that AKTIP partially co-localizes ... [more]
Open Biol Dec. 01, 2015; 6(8); [Pubmed: 27512140]
Throughput
- Low Throughput
Curated By
- BioGRID