BAIT
CHD3
Mi-2a, Mi2-ALPHA, ZFH
chromodomain helicase DNA binding protein 3
GO Process (5)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC25A6
2, 3, AAC3, ANT, ANT 2, ANT 3, ANT3, ANT3Y, RP11-261P4.6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
GO Process (11)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- ADP transport [NAS]
- ATP transport [NAS]
- active induction of host immune response by virus [TAS]
- cellular protein metabolic process [TAS]
- energy reserve metabolic process [TAS]
- modulation by virus of host morphology or physiology [TAS]
- protein targeting to mitochondrion [TAS]
- regulation of insulin secretion [TAS]
- small molecule metabolic process [TAS]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.
CHD3 and CHD4 (Chromodomain Helicase DNA binding protein), two highly similar representatives of the Mi-2 subfamily of SF2 helicases, are coexpressed in many cell lines and tissues and have been reported to act as the motor subunit of the NuRD complex (nucleosome remodeling and deacetylase activities). Besides CHD proteins, NuRD contains several repressors like HDAC1/2, MTA2/3 and MBD2/3, arguing for ... [more]
Nucleic Acids Res. Oct. 13, 2017; 45(18);10534-10554 [Pubmed: 28977666]
Throughput
- High Throughput
Additional Notes
- nuclear extract
Curated By
- BioGRID