BAIT
LARP7
ALAZS, PIP7S, HDCMA18P
La ribonucleoprotein domain family, member 7
GO Process (0)
GO Function (2)
GO Component (4)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NCKAP1
HEM2, NAP1, NAP125, p125Nap1
NCK-associated protein 1
GO Process (7)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- Rac protein signal transduction [IDA]
- apoptotic process [TAS]
- central nervous system development [TAS]
- innate immune response [TAS]
- positive regulation of Arp2/3 complex-mediated actin nucleation [IDA]
- positive regulation of lamellipodium assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.
The transition from transcription initiation to elongation at promoters of primary response genes (PRGs) in metazoan cells is controlled by inducible transcription factors, which utilize P-TEFb to phosphorylate RNA polymerase II (Pol II) in response to stimuli. Prior to stimulation, a fraction of P-TEFb is recruited to promoter-proximal regions in a catalytically inactive state bound to the 7SK small nuclear ... [more]
Mol. Cell Jan. 07, 2016; 61(1);39-53 [Pubmed: 26725010]
Throughput
- High Throughput
Curated By
- BioGRID