TMEM11
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
BNIP3
Gene Ontology Biological Process
- apoptotic process [IPI]
- cell death [ISS]
- cellular response to cobalt ion [IMP]
- cellular response to hypoxia [IMP]
- cellular response to mechanical stimulus [IEP]
- defense response to virus [IDA]
- granzyme-mediated apoptotic signaling pathway [IDA]
- intrinsic apoptotic signaling pathway in response to hypoxia [IMP]
- mitochondrial fragmentation involved in apoptotic process [IDA]
- mitochondrial outer membrane permeabilization [IDA]
- mitochondrial protein catabolic process [IMP]
- negative regulation of apoptotic process [TAS]
- negative regulation of membrane potential [IDA]
- negative regulation of mitochondrial fusion [IDA]
- neuron apoptotic process [ISS]
- positive regulation of apoptotic process [IDA]
- positive regulation of autophagy [TAS]
- positive regulation of mitochondrial fission [IDA]
- positive regulation of programmed cell death [IDA]
- positive regulation of protein complex disassembly [IDA]
- positive regulation of release of cytochrome c from mitochondria [IDA]
- reactive oxygen species metabolic process [IDA]
- regulation of mitochondrial membrane permeability [IDA]
- response to hypoxia [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
High-throughput binary protein interaction mapping is continuing to extend our understanding of cellular function and disease mechanisms. However, we remain one or two orders of magnitude away from a complete interaction map for humans and other major model organisms. Completion will require screening at substantially larger scales with many complementary assays, requiring further efficiency gains in proteome-scale interaction mapping. Here, ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| BNIP3 TMEM11 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9748 | BioGRID | 2246496 | |
| BNIP3 TMEM11 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9461 | BioGRID | 3031640 | |
| BNIP3 TMEM11 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | High | - | BioGRID | - | |
| BNIP3 TMEM11 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 2741407 | |
| BNIP3 TMEM11 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
| BNIP3 TMEM11 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID