LDLRAP1
Gene Ontology Biological Process
- amyloid precursor protein metabolic process [IMP]
- cholesterol homeostasis [IMP]
- cholesterol metabolic process [NAS]
- positive regulation of cholesterol metabolic process [IC]
- positive regulation of receptor-mediated endocytosis [IMP]
- positive regulation of signal transduction [IDA]
- receptor internalization [IMP]
- receptor-mediated endocytosis [IDA]
- receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [IMP]
- regulation of establishment of protein localization to plasma membrane [IMP]
- regulation of protein binding [IMP]
- transport [NAS]
Gene Ontology Molecular Function- AP-2 adaptor complex binding [IDA]
- beta-amyloid binding [IPI]
- clathrin adaptor activity [IDA]
- clathrin binding [IDA]
- low-density lipoprotein particle receptor binding [IPI]
- phosphatidylinositol-4,5-bisphosphate binding [IDA]
- phosphotyrosine binding [IDA]
- protein binding [IPI]
- receptor signaling complex scaffold activity [IMP]
- signaling adaptor activity [IDA]
- AP-2 adaptor complex binding [IDA]
- beta-amyloid binding [IPI]
- clathrin adaptor activity [IDA]
- clathrin binding [IDA]
- low-density lipoprotein particle receptor binding [IPI]
- phosphatidylinositol-4,5-bisphosphate binding [IDA]
- phosphotyrosine binding [IDA]
- protein binding [IPI]
- receptor signaling complex scaffold activity [IMP]
- signaling adaptor activity [IDA]
Gene Ontology Cellular Component
MAPK8IP3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
High-throughput binary protein interaction mapping is continuing to extend our understanding of cellular function and disease mechanisms. However, we remain one or two orders of magnitude away from a complete interaction map for humans and other major model organisms. Completion will require screening at substantially larger scales with many complementary assays, requiring further efficiency gains in proteome-scale interaction mapping. Here, ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| MAPK8IP3 LDLRAP1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 2726902 |
Curated By
- BioGRID