BAIT
PPP3R1
CALNB1, CNB, CNB1
protein phosphatase 3, regulatory subunit B, alpha
GO Process (9)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- apoptotic process [TAS]
- calcineurin-NFAT signaling cascade [IDA]
- dephosphorylation [NAS]
- innate immune response [TAS]
- intrinsic apoptotic signaling pathway [TAS]
- positive regulation of NFAT protein import into nucleus [IDA]
- positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [TAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CHRNA6
CHNRA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
GO Process (5)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
High-throughput binary protein interaction mapping is continuing to extend our understanding of cellular function and disease mechanisms. However, we remain one or two orders of magnitude away from a complete interaction map for humans and other major model organisms. Completion will require screening at substantially larger scales with many complementary assays, requiring further efficiency gains in proteome-scale interaction mapping. Here, ... [more]
Mol. Syst. Biol. Apr. 22, 2016; 12(4);863 [Pubmed: 27107012]
Throughput
- High Throughput
Curated By
- BioGRID