BAIT
FOXP1
12CC4, QRF1, hFKH1B, HSPC215
forkhead box P1
GO Process (24)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- T follicular helper cell differentiation [ISS]
- chemokine (C-C motif) ligand 2 secretion [IDA]
- endothelial cell activation [IMP]
- interleukin-21 secretion [ISS]
- macrophage activation [IDA]
- monocyte activation [IDA]
- negative regulation of B cell apoptotic process [IDA]
- negative regulation of androgen receptor signaling pathway [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- osteoclast development [IDA]
- osteoclast differentiation [IDA]
- positive regulation of endothelial cell migration [IMP]
- positive regulation of smooth muscle cell proliferation [IMP]
- regulation of defense response to bacterium [IDA]
- regulation of endothelial tube morphogenesis [IMP]
- regulation of inflammatory response [IDA]
- regulation of interleukin-1 beta secretion [IDA]
- regulation of interleukin-12 secretion [IDA]
- regulation of macrophage colony-stimulating factor production [IDA]
- regulation of monocyte differentiation [IDA]
- regulation of transcription from RNA polymerase II promoter [IBA]
- regulation of tumor necrosis factor production [IDA]
- response to lipopolysaccharide [IDA]
- transcription from RNA polymerase II promoter [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA]
- nucleus [IDA]
Homo sapiens
PREY
MNAT1
CAP35, MAT1, RNF66, TFB3
MNAT CDK-activating kinase assembly factor 1
GO Process (25)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- 7-methylguanosine mRNA capping [TAS]
- ATP catabolic process [IDA]
- DNA repair [TAS]
- G1/S transition of mitotic cell cycle [TAS]
- G2/M transition of mitotic cell cycle [TAS]
- cell proliferation [TAS]
- gene expression [TAS]
- mitotic cell cycle [TAS]
- nucleotide-excision repair [TAS]
- nucleotide-excision repair, DNA damage removal [TAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- positive regulation of viral transcription [TAS]
- protein complex assembly [TAS]
- protein phosphorylation [IDA]
- regulation of cyclin-dependent protein serine/threonine kinase activity [TAS]
- regulation of transcription from RNA polymerase II promoter [IDA]
- termination of RNA polymerase I transcription [TAS]
- transcription elongation from RNA polymerase I promoter [TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase I promoter [TAS]
- transcription from RNA polymerase II promoter [IDA, TAS]
- transcription initiation from RNA polymerase I promoter [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
- transcription-coupled nucleotide-excision repair [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
High-throughput binary protein interaction mapping is continuing to extend our understanding of cellular function and disease mechanisms. However, we remain one or two orders of magnitude away from a complete interaction map for humans and other major model organisms. Completion will require screening at substantially larger scales with many complementary assays, requiring further efficiency gains in proteome-scale interaction mapping. Here, ... [more]
Mol. Syst. Biol. Apr. 22, 2016; 12(4);863 [Pubmed: 27107012]
Throughput
- High Throughput
Curated By
- BioGRID