Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

FAM188B enhances cell survival via interaction with USP7.

Choi ES, Lee H, Sung JY, Lee CH, Jang H, Kim KT, Kim YN, Kim HP, Goh SH

We have previously reported that FAM188B showed significant differential exon usage in cancers (NCBI GEO GSE30727), but the expression and function of FAM188B is not well characterized. In the present study, we explored the functions of FAM188B by a knockdown strategy, using siRNAs specific for FAM188B in colon cancer cell lines. FAM188B is a novel gene that encodes a protein ... [more]

Cell Death Dis May. 24, 2018; 9(6);633 [Pubmed: 29795372]

Throughput

  • High Throughput

Curated By

  • BioGRID