BAIT
RPM1
DISEASE RESISTANCE PROTEIN RPM1, RESISTANCE TO P. SYRINGAE PV MACULICOLA 1, RESISTANCE TO PSEUDOMONAS SYRINGAE 3, RPS3, AT3G07040
disease resistance protein RPM1
GO Process (2)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Arabidopsis thaliana (Columbia)
PREY
RIN4
RPM1 interacting protein 4, AT3G25070
RPM1 interacting protein 4
GO Process (6)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- defense response signaling pathway, resistance gene-independent [IMP]
- defense response to bacterium, incompatible interaction [IMP]
- negative regulation of plant-type hypersensitive response [IMP]
- plant-type hypersensitive response [IMP]
- protein phosphorylation [IDA]
- response to molecule of bacterial origin [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Arabidopsis thaliana (Columbia)
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis.
In Arabidopsis, RPM1 confers resistance against Pseudomonas syringae expressing either of two sequence unrelated type III effectors, AvrRpm1 or AvrB. An RPM1-interacting protein (RIN4) coimmunoprecipitates from plant cell extracts with AvrB, AvrRpm1, or RPM1. Reduction of RIN4 protein levels inhibits both the hypersensitive response and the restriction of pathogen growth controlled by RPM1. RIN4 reduction causes diminution of RPM1. RIN4 ... [more]
Cell Mar. 22, 2002; 108(6);743-54 [Pubmed: 11955429]
Throughput
- Low Throughput