BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
ADD1
adducin 1 (alpha)
GO Process (16)
GO Function (9)
GO Component (14)
Gene Ontology Biological Process
- actin filament bundle assembly [ISO]
- barbed-end actin filament capping [ISO]
- cell morphogenesis [ISO]
- cell volume homeostasis [ISO]
- cellular response to retinoic acid [IDA]
- cytoskeleton organization [TAS]
- erythrocyte differentiation [ISO]
- hemoglobin metabolic process [ISO]
- homeostasis of number of cells within a tissue [ISO]
- in utero embryonic development [ISO]
- ion transport [NAS]
- multicellular organism growth [ISO]
- negative regulation of actin filament polymerization [IMP]
- positive regulation of angiogenesis [IDA]
- positive regulation of endocytosis [IMP]
- positive regulation of protein binding [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- F-actin capping protein complex [ISO]
- cell [ISO]
- cytoskeleton [ISO]
- dendrite [IDA]
- dendritic spine [IDA]
- focal adhesion [ISO]
- intermediate filament cytoskeleton [ISO]
- membrane [ISO]
- nucleoplasm [ISO]
- nucleus [ISO]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [ISO]
- postsynaptic density [IDA]
- synapse [IDA]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID