BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
CAMK2B
Ck2b
calcium/calmodulin-dependent protein kinase II beta
GO Process (17)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [ISO]
- activation of meiosis involved in egg activation [ISO]
- calcium ion transport [ISO]
- cell projection morphogenesis [IMP]
- inhibitory G-protein coupled receptor phosphorylation [ISO]
- long-term synaptic potentiation [IMP]
- neuromuscular process controlling balance [ISO]
- peptidyl-serine phosphorylation [ISO]
- positive regulation of apoptotic signaling pathway [ISO]
- positive regulation of dendritic spine morphogenesis [IMP]
- positive regulation of neuron projection development [IMP]
- positive regulation of phospholipase A2 activity [IDA]
- positive regulation of synapse maturation [IMP]
- protein autophosphorylation [ISO, ISS]
- regulation of long-term neuronal synaptic plasticity [ISO]
- regulation of synaptic transmission, cholinergic [ISO]
- response to cadmium ion [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID