BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
CSNK2A1
casein kinase 2, alpha 1 polypeptide
GO Process (10)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO, ISS]
- positive regulation of Wnt signaling pathway [ISO, ISS]
- positive regulation of cell growth [ISO, ISS]
- positive regulation of cell proliferation [ISO, ISS]
- positive regulation of protein catabolic process [ISO, ISS]
- protein autophosphorylation [ISO]
- protein phosphorylation [ISO, ISS]
- regulation of catalytic activity [ISO]
- regulation of cell growth [NAS]
- regulation of cell proliferation [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID