BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
C3
complement component 3
GO Process (22)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- blood coagulation [IMP]
- complement activation [IDA, ISO]
- complement activation, classical pathway [TAS]
- positive regulation of ERK1 and ERK2 cascade [IDA]
- positive regulation of G-protein coupled receptor protein signaling pathway [ISO, ISS]
- positive regulation of activation of membrane attack complex [ISO]
- positive regulation of angiogenesis [ISO]
- positive regulation of apoptotic cell clearance [ISO]
- positive regulation of developmental growth [IDA]
- positive regulation of glucose transport [ISO, ISS]
- positive regulation of lipid storage [ISO, ISS]
- positive regulation of phagocytosis [ISO]
- positive regulation of protein phosphorylation [ISO, ISS]
- positive regulation of type IIa hypersensitivity [ISO]
- positive regulation vascular endothelial growth factor production [ISO]
- regulation of triglyceride biosynthetic process [ISO, ISS]
- response to estradiol [IEP]
- response to estrogen [IEP]
- response to glucocorticoid [IEP]
- response to magnesium ion [IEP]
- response to progesterone [IEP]
- tolerance induction [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID