BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
C1QBP
Habp1, gC1qR
complement component 1, q subcomponent binding protein
GO Process (19)
GO Function (10)
GO Component (7)
Gene Ontology Biological Process
- immune response [TAS]
- mature ribosome assembly [ISO, ISS]
- negative regulation of MDA-5 signaling pathway [ISO, ISS]
- negative regulation of RIG-I signaling pathway [ISO, ISS]
- negative regulation of defense response to virus [ISO, ISS]
- negative regulation of interferon-gamma production [ISO, ISS]
- negative regulation of interleukin-12 production [ISO, ISS]
- negative regulation of mRNA splicing, via spliceosome [ISO, ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISO, ISS]
- phosphatidylinositol 3-kinase signaling [ISO, ISS]
- positive regulation of apoptotic process [ISO, ISS]
- positive regulation of cell adhesion [ISO, ISS]
- positive regulation of dendritic cell chemotaxis [ISO, ISS]
- positive regulation of mitochondrial translation [ISO, ISS]
- positive regulation of neutrophil chemotaxis [ISO, ISS]
- positive regulation of protein kinase B signaling [ISO, ISS]
- positive regulation of substrate adhesion-dependent cell spreading [ISO, ISS]
- positive regulation of trophoblast cell migration [ISO, ISS]
- regulation of complement activation [ISO, ISS]
Gene Ontology Molecular Function- adrenergic receptor binding [IDA]
- complement component C1q binding [IDA, ISO]
- hyaluronic acid binding [ISO, ISS]
- kininogen binding [ISO, ISS]
- mRNA binding [ISO, ISS]
- mitochondrial ribosome binding [ISO, ISS]
- protein binding [IPI]
- protein kinase C binding [IDA]
- transcription corepressor activity [ISO, ISS]
- transcription factor binding [ISO]
- adrenergic receptor binding [IDA]
- complement component C1q binding [IDA, ISO]
- hyaluronic acid binding [ISO, ISS]
- kininogen binding [ISO, ISS]
- mRNA binding [ISO, ISS]
- mitochondrial ribosome binding [ISO, ISS]
- protein binding [IPI]
- protein kinase C binding [IDA]
- transcription corepressor activity [ISO, ISS]
- transcription factor binding [ISO]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID