BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
SLC1A3
EAAT1, GLAST, GLAST-1, GluT-1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
GO Process (21)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- D-aspartate import [ISO]
- L-glutamate import [ISO]
- L-glutamate transmembrane transport [IDA, IMP, ISO, TAS]
- L-glutamate transport [IDA, IMP, ISO]
- auditory behavior [ISO]
- cell morphogenesis involved in neuron differentiation [ISO]
- cranial nerve development [ISO]
- gamma-aminobutyric acid biosynthetic process [ISO]
- glutamate biosynthetic process [ISO]
- glutamate metabolic process [ISO]
- malate-aspartate shuttle [IDA]
- neuromuscular process controlling balance [ISO]
- neurotransmitter transport [TAS]
- positive regulation of synaptic transmission [ISO]
- response to antibiotic [ISO]
- response to drug [ISO]
- response to inorganic substance [IDA]
- response to light stimulus [ISO]
- response to wounding [ISO]
- sensory perception of sound [ISO]
- sodium ion transmembrane transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID