BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
HOMER1
HOMER1F, Vesl-1
homer homolog 1 (Drosophila)
GO Process (14)
GO Function (9)
GO Component (14)
Gene Ontology Biological Process
- G-protein coupled glutamate receptor signaling pathway [IDA]
- behavioral response to cocaine [ISO]
- chemical homeostasis within a tissue [ISO]
- circadian rhythm [IEP]
- positive regulation of calcium ion transport [ISO]
- protein localization to synapse [IDA]
- regulation of calcium ion import [ISO]
- regulation of cation channel activity [ISO]
- regulation of store-operated calcium entry [IBA, ISO]
- response to calcium ion [ISO]
- response to cocaine [IEP]
- response to nicotine [IEP]
- skeletal muscle contraction [ISO]
- skeletal muscle fiber development [ISO]
Gene Ontology Molecular Function- G-protein coupled glutamate receptor binding [IPI]
- identical protein binding [IPI]
- ion channel binding [ISO]
- protein binding [IPI]
- protein complex scaffold [IPI]
- protein heterodimerization activity [IPI]
- receptor binding [IDA]
- scaffold protein binding [IPI]
- type 5 metabotropic glutamate receptor binding [IPI]
- G-protein coupled glutamate receptor binding [IPI]
- identical protein binding [IPI]
- ion channel binding [ISO]
- protein binding [IPI]
- protein complex scaffold [IPI]
- protein heterodimerization activity [IPI]
- receptor binding [IDA]
- scaffold protein binding [IPI]
- type 5 metabotropic glutamate receptor binding [IPI]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID