BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
NEFL
NF-L, Nfl
neurofilament, light polypeptide
GO Process (21)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- anterograde axon cargo transport [ISO]
- axon transport of mitochondrion [ISO]
- intermediate filament bundle assembly [ISO]
- intermediate filament organization [ISO]
- locomotion [ISO]
- microtubule cytoskeleton organization [ISO]
- negative regulation of neuron apoptotic process [ISO]
- neurofilament bundle assembly [ISO]
- neurofilament cytoskeleton organization [ISO]
- neuromuscular process controlling balance [ISO]
- neuron projection morphogenesis [ISO]
- peripheral nervous system axon regeneration [ISO]
- positive regulation of axonogenesis [ISO]
- protein polymerization [IDA]
- regulation of axon diameter [ISO]
- response to corticosterone [IEP]
- response to organic substance [IEP]
- response to organonitrogen compound [IEP]
- response to peptide hormone [IEP]
- response to toxic substance [IEP]
- retrograde axon cargo transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID